Hi all, can I please pick your brains?
I had a really good response to Humra, ESR went down to 20 and I was singing and dancing.
3 months in I have had a horrible flare, ESR back at 50 and more worrying GFR had a bit of a nose dive down to 38 from 46. ( I have chronic kidney disease with proteinuria, haematuria, hypertension, high creatinine and low GFR which is being monitred)
My rheumy nurse says that some people on Humira get flares and general ups and downs; but in others after an initial good result the body finds a way of circumnavigating the drug. This seems to make sense and we are waiting a month or so to see if I pick up again.
However I am also waiting to hear back from my rheumy consultant about the possible effect on my kidney function and what to do about that.
Has anyone else had to come off an anti-tnf because of kidney side effects and / or has anyone had flares etc after intial good response?
(please ignore esr numbers - don't want to go down that route, just put them there to indicate the difference!!!

)
I really, really don't want to abandon it yet.
many thanks
Alison